About the Pharmacy Board Exam
Exam Structure
- Administered by PRC Board of Pharmacy
- Covers 5 major pharmacy areas
- Multiple-choice format
- Passing rate: 75% overall
- Governed by RA 10918 (Philippine Pharmacy Act)
Major Pharmacy Areas
- Pharmaceutical Chemistry
- Pharmacology
- Pharmaceutics
- Clinical Pharmacy
- Pharmacy Practice & Management
Fresh Questions Every Time
Our questions are constantly updated and randomized. No two quiz sessions are the same, ensuring a unique learning experience each time you practice. This helps you prepare more effectively by exposing you to varied question formats.
Pharmaceutical Chemistry
Medicinal chemistry, drug synthesis, and chemical analysis
Topics Covered (6)
- Medicinal Chemistry Principles
- Drug Structure and Activity
- Chemical Analysis Methods
- Drug Synthesis and Metabolism
- Analytical Techniques (HPLC, GC)
- Organic Chemistry Applications
Pharmacology
Drug mechanisms, therapeutic uses, and adverse effects
Topics Covered (6)
- Drug Mechanisms of Action
- Pharmacokinetics and Pharmacodynamics
- Adverse Drug Reactions
- Drug Interactions
- Therapeutic Drug Monitoring
- Clinical Pharmacology
Pharmaceutics
Drug formulation, dosage forms, and compounding
Topics Covered (6)
- Dosage Form Design
- Pharmaceutical Excipients
- Drug Formulation Techniques
- Compounding Principles
- Quality Control and Assurance
- Pharmaceutical Manufacturing
Clinical Pharmacy
Patient care, drug therapy management, and counseling
Topics Covered (6)
- Medication Therapy Management (MTM)
- Patient Counseling and Education
- Drug Therapy Monitoring
- Clinical Decision Making
- Pharmacotherapy Guidelines
- Adverse Event Management
Pharmacy Practice & Management
Pharmacy laws, ethics, and business management
Topics Covered (6)
- Philippine Pharmacy Act (RA 10918)
- Dangerous Drugs Act (RA 9165)
- Generics Act (RA 9502)
- Good Pharmacy Practice (GPP)
- Pharmacy Ethics and Professional Conduct
- Pharmacy Business Management
Comprehensive Pharmacy Board Exam Study Guide
๐ 3-Month Study Timeline
| Month | Focus Areas | Key Activities |
|---|---|---|
| Month 1 | Pharmaceutical Chemistry & Pharmacology | Study drug classifications, mechanisms of action, medicinal chemistry principles, practice pharmaceutical calculations |
| Month 2 | Pharmaceutics & Clinical Pharmacy | Master dosage forms, formulation techniques, compounding, MTM, patient counseling, pharmacotherapy protocols |
| Month 3 | Pharmacy Practice & Review | Memorize RA 10918, RA 9165, RA 9502, GPP guidelines, comprehensive review, practice exams, mock tests |
๐ Essential Drug Classifications (High-Yield for Exam)
| Drug Class | Key Examples | Mechanism of Action | Major Adverse Effects |
|---|---|---|---|
| ACE Inhibitors | Enalapril, Lisinopril, Captopril | Inhibit ACE, decrease angiotensin II | Dry cough, hyperkalemia, angioedema |
| Beta-Blockers | Metoprolol, Atenolol, Propranolol | Block beta-adrenergic receptors | Bradycardia, fatigue, bronchospasm |
| Statins | Atorvastatin, Simvastatin, Rosuvastatin | Inhibit HMG-CoA reductase | Myopathy, rhabdomyolysis, elevated liver enzymes |
| NSAIDs | Ibuprofen, Naproxen, Diclofenac | Inhibit COX-1 and COX-2 enzymes | GI bleeding, renal impairment, CV events |
| Proton Pump Inhibitors | Omeprazole, Pantoprazole, Esomeprazole | Inhibit H+/K+ ATPase pump | Headache, C. difficile infection, osteoporosis |
| Antibiotics (Penicillins) | Amoxicillin, Ampicillin, Penicillin G | Inhibit bacterial cell wall synthesis | Allergic reactions, diarrhea, rash |
| Diuretics (Loop) | Furosemide, Bumetanide, Torsemide | Inhibit Na-K-2Cl cotransporter in Loop of Henle | Hypokalemia, ototoxicity, dehydration |
| Antidiabetics (Biguanides) | Metformin | Decrease hepatic glucose production | GI upset, lactic acidosis (rare), vitamin B12 deficiency |
๐ข Essential Pharmaceutical Calculations
1. Dose Calculations
Formula: Dose = (Desired Dose / Stock Strength) ร Volume
Example: Order 500mg, Stock 250mg/5mL โ (500/250) ร 5 = 10 mL
2. IV Drip Rate
Formula: Drops/min = (Volume ร Drop Factor) / Time (min)
Example: 1000mL over 8h, 20 gtts/mL โ (1000ร20)/(8ร60) = 42 gtts/min
3. Dilutions (C1V1 = C2V2)
Formula: CโVโ = CโVโ
Example: Dilute 100mL of 70% alcohol to 50% โ (70ร100) = (50รVโ), Vโ = 140mL
4. Alligation Method
Use: Mix two concentrations to get desired strength
Draw diagonal lines, calculate parts needed of each concentration
5. Body Surface Area (BSA)
Mosteller Formula: BSA (mยฒ) = โ[(Height(cm) ร Weight(kg)) / 3600]
Used for chemotherapy and pediatric dosing
6. Creatinine Clearance (CrCl)
Cockcroft-Gault: CrCl = [(140-age) ร weight] / (72 ร SCr) ร 0.85 (if female)
Used for renal dose adjustments
๐งช Common Dosage Forms & Pharmaceutical Excipients
Solid Dosage Forms
- Tablets: Compressed powders (immediate, sustained, enteric-coated)
- Capsules: Hard gelatin (powder/granules), soft gelatin (liquids)
- Powders: Bulk, divided, effervescent
- Granules: Coarse particles for reconstitution or compression
Liquid Dosage Forms
- Solutions: Clear, homogeneous mixtures (syrups, elixirs, tinctures)
- Suspensions: Dispersed solid particles (shake well before use)
- Emulsions: Oil-in-water or water-in-oil (creams, lotions)
- Injections: Parenteral (IV, IM, SC) - sterile, pyrogen-free
Key Excipients (Pharmaceutics)
- Binders: PVP, starch, cellulose (tablet cohesion)
- Disintegrants: Sodium starch glycolate, croscarmellose (tablet breakup)
- Lubricants: Magnesium stearate, talc (reduce friction)
- Preservatives: Methylparaben, benzalkonium chloride (antimicrobial)
Quality Control Tests
- Dissolution Test: Rate of drug release from dosage form
- Disintegration Test: Time for tablet to break apart
- Uniformity of Content: Drug content consistency
- Sterility Test: Absence of microorganisms (parenterals)
โ๏ธ Philippine Pharmacy Laws (Memorization Priority)
RA 10918 - Philippine Pharmacy Act (2016)
- Defines practice of pharmacy, registration, and licensing requirements
- Establishes PRC Board of Pharmacy with 5 members (3-year terms)
- Requires bachelor's degree in pharmacy and passing PLE for licensure
- Mandates continuing professional development (CPD) for license renewal
- Defines ownership: Only licensed pharmacists can own community pharmacies
- Penalty: Illegal practice punishable by fine (โฑ200,000-โฑ500,000) or imprisonment (2-5 years)
RA 9165 - Comprehensive Dangerous Drugs Act (2002)
- Regulates dangerous drugs (Schedule I-IV) and controlled precursors
- Requires S2 License from PDEA for pharmacies dispensing controlled substances
- Mandates recordkeeping for dangerous drugs (separate logbook, 2 years)
- Prescription requirements: Physician's signature, patient details, date
- Penalty: Unauthorized sale/possession punishable by life imprisonment + fines
- Special provisions: Mandatory drug testing for students, employees, applicants
RA 9502 - Universally Accessible Cheaper and Quality Medicines Act (2008)
- Promotes use of generic drugs (mandatory generic name on prescriptions)
- Pharmacists must inform patients of cheaper generic alternatives
- Maximum Drug Retail Prices (MDRP) for selected drugs
- Parallel importation allowed to reduce drug prices
- Penalty: Non-compliance fined โฑ50,000-โฑ200,000 or imprisonment (6 months-2 years)
Good Pharmacy Practice (GPP) - WHO Standards
- Patient-centered care: Counseling, medication therapy management
- Quality assurance: Proper storage (temperature, light, humidity control)
- Professional competence: CPD, evidence-based practice
- Ethical conduct: Patient confidentiality, informed consent, conflict of interest avoidance
๐ฅ Clinical Pharmacy & Medication Therapy Management (MTM)
SOAP Note Format (Clinical Documentation)
- S (Subjective): Patient complaints, symptoms ("I feel dizzy")
- O (Objective): Vital signs, lab results (BP 140/90, K+ 3.2)
- A (Assessment): Diagnosis, drug therapy problems (hypokalemia)
- P (Plan): Interventions (start K supplement, monitor levels)
Drug-Related Problems (DRPs)
- Indication: Untreated condition, unnecessary drug therapy
- Effectiveness: Wrong drug, dose too low, drug resistance
- Safety: Adverse drug reaction, dose too high, toxicity
- Adherence: Patient not taking medication as prescribed
Pharmacokinetic Parameters (PK/PD)
- Absorption: Bioavailability (F), first-pass metabolism
- Distribution: Volume of distribution (Vd), protein binding
- Metabolism: CYP450 enzymes (CYP3A4, CYP2D6), Phase I & II
- Excretion: Renal clearance, half-life (tยฝ), elimination
Common Drug Interactions (High-Yield)
- Warfarin + NSAIDs: โ bleeding risk (avoid or monitor INR closely)
- Statins + Azole antifungals: โ myopathy risk (CYP3A4 inhibition)
- ACE inhibitors + K-sparing diuretics: โ hyperkalemia risk
- Digoxin + Loop diuretics: โ digoxin toxicity (hypokalemia)
๐ฏ Exam Day Strategies & Tips
Before the Exam
- โ Review drug suffixes (-pril, -olol, -statin) for quick drug class identification
- โ Memorize top 200 drugs by generic/brand name
- โ Practice pharmaceutical calculations daily (30 min)
- โ Create flashcards for RA 10918, RA 9165, RA 9502 key provisions
- โ Review common drug interactions and contraindications
- โ Sleep 7-8 hours the night before the exam
During the Exam
- โ Read questions carefully - identify what is being asked
- โ Eliminate obviously wrong answers first (process of elimination)
- โ For calculations: Write down formula, units, show your work
- โ Clinical scenarios: Think patient safety first (ABCDE approach)
- โ Time management: Don't spend >2 min per question
- โ Review flagged questions if time permits
๐ Recommended Study Materials
- โข Pharmacology: Katzung's Basic & Clinical Pharmacology, Lippincott Illustrated Reviews
- โข Pharmaceutics: Remington: The Science and Practice of Pharmacy
- โข Medicinal Chemistry: Foye's Principles of Medicinal Chemistry
- โข Laws: Full text of RA 10918, RA 9165, RA 9502 (Official Gazette)
- โข Practice Questions: PinoyReviewer.com (this site), PLE review centers
Complete Pharmacy Board Exam Coverage
5 major pharmacy categories with 50+ practice questions with detailed explanations. Questions cover all competencies required by the PRC Board of Pharmacy.